The lack of endothelization after drug-eluting stent implantation as a cause of fatal late stent thrombosis

J Thromb Thrombolysis. 2008 Oct;26(2):154-8. doi: 10.1007/s11239-007-0080-2. Epub 2007 Aug 29.

Abstract

The authors present a fatal case of late thrombosis of paclitaxel-eluting stent implanted in the left main stem occurring 6 months after the procedure and 3 weeks after the cessation of clopidogrel. An autopsy has shown the lack of endothelization of deployed stent.

Publication types

  • Case Reports

MeSH terms

  • Angioplasty, Balloon, Coronary / adverse effects
  • Angioplasty, Balloon, Coronary / instrumentation*
  • Autopsy
  • Cardiovascular Agents / administration & dosage*
  • Clopidogrel
  • Coronary Angiography
  • Drug-Eluting Stents*
  • Endothelial Cells / pathology*
  • Fatal Outcome
  • Humans
  • Male
  • Middle Aged
  • Myocardial Infarction / diagnostic imaging
  • Myocardial Infarction / therapy*
  • Paclitaxel / administration & dosage*
  • Platelet Aggregation Inhibitors / therapeutic use
  • Prosthesis Design
  • Thrombosis / etiology*
  • Thrombosis / pathology
  • Ticlopidine / analogs & derivatives
  • Ticlopidine / therapeutic use
  • Treatment Outcome

Substances

  • Cardiovascular Agents
  • Platelet Aggregation Inhibitors
  • Clopidogrel
  • Ticlopidine
  • Paclitaxel