A comparative study of different artefact removal algorithms for EEG signals acquired during functional MRI

Neuroimage. 2007 Oct 15;38(1):124-37. doi: 10.1016/j.neuroimage.2007.07.025. Epub 2007 Aug 7.

Abstract

In electroencephalographic (EEG) measurements performed during functional Magnetic Resonance Imaging (fMRI), imaging and cardiac artefacts strongly contaminate the EEG signal. Several algorithms have been proposed to suppress these artefacts and most of them have shown important improvements with respect to uncorrected signals. However, the relative performances of these algorithms have not been properly assessed. In particular, it is not known to what extent such algorithms deteriorate the EEG signal of interest. In this study, we propose to cross-validate different methods proposed for artefact correction, using a forward model to generate EEG and MR-related artefacts. The methods are assessed under various experimental conditions (described in terms of EEG sampling rate, artefacts amplitude, frequency band of interest, etc.). Using experimental data, we also tested the performance of the correction methods for alpha rhythm imaging and for epileptic spike reconstruction. Results show that most of the methods allow the observation of the modulation of alpha rhythms and the identification of spikes, despite subtle differences between algorithms. They also show that over-filtering the data may degrade the EEG. Our results indicate that the optimal artefact removal technique should be chosen according to whether one is interested in fast (>10 Hz) vs. slow (<10 Hz) oscillations or in evoked vs. ongoing activity.

Publication types

  • Comparative Study
  • Evaluation Study

MeSH terms

  • Adult
  • Algorithms*
  • Artifacts*
  • Brain Mapping / methods
  • Diagnosis, Computer-Assisted / methods*
  • Electroencephalography / methods*
  • Epilepsy / diagnosis*
  • Humans
  • Magnetic Resonance Imaging / methods*
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Software Validation
  • Software*