Gelatin microspheres: initial clinical experience for the transcatheter arterial embolization

Eur J Radiol. 2008 Sep;67(3):536-40. doi: 10.1016/j.ejrad.2007.07.021. Epub 2007 Sep 7.

Abstract

Purpose: The purpose of this study is to evaluate the embolization effects of gelatin microspheres (GMSs) when used as an embolic material for transcatheter arterial embolization (TAE) for several organs.

Materials and methods: We prepared GMSs that dissolves in 5 days in extravasuclar tissue. GMSs were used in five cases in total, four cases with multiple liver tumors and one case with a pelvic bone tumor.

Results: In all five cases, it was possible to treat the targeted tumors by TAE with GMSs. In the contrast-enhanced CT performed 2-4 weeks later, the embolized tumors did not show an enhancement effect. Passage of GMSs in the microcatheter was excellent.

Conclusion: GMSs showed sufficient potential to be used as an embolic material.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Catheterization, Peripheral / methods*
  • Embolization, Therapeutic / instrumentation
  • Embolization, Therapeutic / methods*
  • Female
  • Gelatin / therapeutic use*
  • Humans
  • Male
  • Microspheres
  • Middle Aged
  • Peripheral Vascular Diseases / therapy*
  • Pilot Projects

Substances

  • Gelatin