A case of mixed intoxication with isopropyl alcohol and propanol-1 after ingestion of a topical antiseptic solution

Clin Toxicol (Phila). 2007 Sep;45(6):701-4. doi: 10.1080/15563650701517285.

Abstract

We report a mixed intoxication with isopropyl alcohol and propanol-1 in a hospitalized patient who ingested, on two separate days, two 100 ml bottles of a topical antiseptic solution containing isopropyl alcohol and propanol-1. Eight hours after the second ingestion, plasma concentrations of isopropanol, propanol-1 and acetone were 37 mg/dL, <10 mg/dL, and 227 mg/dl, respectively. Despite a lack of severe toxicity, 4-methylpyrazole (fomepizole) was initiated. This case points out the need to limit access to alcohol-containing antiseptic solutions on wards where alcoholic and psychotic patients are hospitalized.

Publication types

  • Case Reports

MeSH terms

  • 1-Propanol / poisoning*
  • 2-Propanol / poisoning*
  • Adult
  • Anti-Infective Agents, Local / poisoning*
  • Antidotes / administration & dosage
  • Antidotes / therapeutic use
  • Drug Combinations
  • Female
  • Fomepizole
  • Humans
  • Poisoning / drug therapy
  • Pyrazoles / administration & dosage
  • Pyrazoles / therapeutic use
  • Suicide, Attempted / psychology
  • Treatment Outcome

Substances

  • Anti-Infective Agents, Local
  • Antidotes
  • Drug Combinations
  • Pyrazoles
  • Fomepizole
  • 1-Propanol
  • 2-Propanol