Accurate measurement of the distance separating two adjacent sheet structures, such as femoral cartilage and acetabular cartilage in the hip joint is important in evaluation of osteoarthritis. A new method, insensitive to the influence of adjacent sheet structures, was developed to improve the accuracy of hip cartilage thickness measurement. A theoretical simulation for investigating the influence of adjacent sheet structures on the accuracy of cartilage thickness measurement in MR images was performed. The thickness is defined as the distance between zero-crossings of the second directional derivatives along the sheet surface normal direction. The simulation measurement showed considerable underestimation in thickness measurement occurred due to the influence of the adjacent sheet. A new method based on a model of the MR imaging process to eliminate the influence of adjacent sheet structure was developed and tested using phantoms and two cadaveric human hip joint MR scans. The new method reduced the influence of the adjacent sheet structure was more accurate than the conventional method for measuring hip cartilage thickness.