Four-dimensional multislice helical CT of the lung: qualitative comparison of retrospectively gated and static images in an ex-vivo system

Radiother Oncol. 2007 Nov;85(2):215-22. doi: 10.1016/j.radonc.2007.09.003. Epub 2007 Oct 17.

Abstract

Purpose: To analyse the image quality of retrospectively gated helical CT using controlled respiratory motion of porcine lung explants.

Materials and methods: Five porcine lungs were examined inside a chest phantom. A silicone membrane was rhythmically inflated and deflated to simulate diaphragmatic respiration. Dynamic images (regular respiration at 8/min) and static scans (w/o respiration) at 0/25/50/75 and 100% of maximum inspiration were acquired with a 40-row detector CT scanner (rotation time 1s, pitch 0.1). Image quality on multi-planar reformations was evaluated by two observers. Partial projection artifacts, stepladder-artifacts and noise were compared for upper, middle and lower parts of the lung and different respiratory phases (scores 0-3 for absent, minimal, moderate and diagnostically relevant artifacts).

Results: Partial projection effects were limited to dynamic scans (mean score 1.33). Stepladder artifacts predominated in dynamic series compared to static series (mean score 0.55 versus 0.1; p<0.001). Image noise was not related to lung motion (mean scores 0.68-0.81). All artifacts predominated close to the diaphragm compared to the upper and middle parts of the lung (p<0.001 to p=0.02, respectively). Partial projection and stepladder artifacts were less in end-inspiration and end-expiration than within the respiration (p<0.001 and p=0.17, respectively). Diagnostically relevant artifacts were noted 9 times (9/9 close to diaphragm, 7/9 partial-projection).

Conclusions: Even in ideal realistic conditions, helical 4D-CT produced tolerable artifacts which could be overcome by radiologists.

Publication types

  • Comparative Study

MeSH terms

  • Lung / diagnostic imaging*
  • Lung / physiology
  • Phantoms, Imaging
  • Respiration*
  • Retrospective Studies
  • Tomography, Spiral Computed / methods*