A patient treated with olanzapine developing diabetes de novo: proposal for hyperglycaemia screening

Neth J Med. 2007 Oct;65(9):346-8.

Abstract

We report a patient with schizophrenia who developed diabetes mellitus during treatment with olanzapine. The case confirms the pattern of atypical antipsychotic-related diabetic emergencies: rapid onset in relatively young patients, often with severe glucose derangements and serious complications. As diabetic emergencies have a high morbidity and mortality, regular glucose screening should be performed in patients with schizophrenia treated with atypical antipsychotics.

Publication types

  • Case Reports

MeSH terms

  • Antipsychotic Agents / adverse effects
  • Antipsychotic Agents / therapeutic use
  • Benzodiazepines / adverse effects*
  • Benzodiazepines / therapeutic use
  • Black People
  • Diabetes Mellitus, Type 2 / chemically induced*
  • Diabetes Mellitus, Type 2 / complications
  • Diabetes Mellitus, Type 2 / drug therapy
  • Humans
  • Male
  • Middle Aged
  • Netherlands
  • Olanzapine
  • Schizophrenia, Paranoid / drug therapy*

Substances

  • Antipsychotic Agents
  • Benzodiazepines
  • Olanzapine