Direct generation of ES-like cells from unmodified mouse embryonic fibroblasts by Oct4/Sox2/Myc/Klf4

Cell Res. 2007 Nov;17(11):959-62. doi: 10.1038/cr.2007.92.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cells, Cultured
  • DNA-Binding Proteins* / biosynthesis
  • DNA-Binding Proteins* / genetics
  • Embryo, Mammalian / cytology*
  • Embryo, Mammalian / metabolism
  • Embryonic Stem Cells / cytology*
  • Embryonic Stem Cells / metabolism
  • Fibroblasts / cytology*
  • Fibroblasts / metabolism
  • Kruppel-Like Factor 4
  • Kruppel-Like Transcription Factors* / biosynthesis
  • Kruppel-Like Transcription Factors* / genetics
  • Mice
  • Octamer Transcription Factor-3* / biosynthesis
  • Octamer Transcription Factor-3* / genetics
  • Proto-Oncogene Proteins c-myc* / biosynthesis
  • Proto-Oncogene Proteins c-myc* / genetics
  • Retroviridae
  • SOXB1 Transcription Factors
  • Trans-Activators* / biosynthesis
  • Trans-Activators* / genetics
  • Transduction, Genetic

Substances

  • DNA-Binding Proteins
  • Klf4 protein, mouse
  • Kruppel-Like Factor 4
  • Kruppel-Like Transcription Factors
  • Myc protein, mouse
  • Octamer Transcription Factor-3
  • Pou5f1 protein, mouse
  • Proto-Oncogene Proteins c-myc
  • SOXB1 Transcription Factors
  • Sox2 protein, mouse
  • Trans-Activators