Enhancing the reactivity of 1,2,3-triazoles in "click" macrocycles by face-to-face dibenzylammonium ion binding

Yi Liu; Xiyun Zhang; Liana M Klivansky; Gayane Koshkakaryan

doi:10.1039/b711505a

Enhancing the reactivity of 1,2,3-triazoles in "click" macrocycles by face-to-face dibenzylammonium ion binding

Chem Commun (Camb). 2007 Dec 7:(45):4773-5. doi: 10.1039/b711505a. Epub 2007 Oct 23.

Authors

Yi Liu¹, Xiyun Zhang, Liana M Klivansky, Gayane Koshkakaryan

Affiliation

¹ The Molecular Foundry, Lawrence Berkeley National Laboratory, One Cyclotron Road, MS 67R6110, Berkeley, CA 94720, USA.

PMID: 18004437
DOI: 10.1039/b711505a

Abstract

A face-to-face binding motif between dibenzylammonium ions and macrocycles containing 1,2,3-triazoles was established, which operates cooperatively to enhance the reactivity of 1,2,3-triazoles in an Arbuzov-type dealkylation reaction.