Antiphospholipid syndrome associated with human herpesvirus-6 infection

Pediatr Neurol. 2007 Dec;37(6):449-51. doi: 10.1016/j.pediatrneurol.2007.08.016.

Abstract

The case of a patient with basal ganglia infarction associated with primary human herpesvirus-6 infection is reported. Anticardiolipin antibody immunoglobulin G was elevated after human herpesvirus-6 infection and then decreased gradually. The transient elevation in the antiphospholipid antibody level suggests that the human herpesvirus-6 infection can induce antiphospholipid syndrome, thus resulting in a cerebral infarction.

Publication types

  • Case Reports

MeSH terms

  • Antibodies / blood
  • Antiphospholipid Syndrome / blood
  • Antiphospholipid Syndrome / diagnosis
  • Antiphospholipid Syndrome / etiology*
  • Antiphospholipid Syndrome / virology*
  • Cardiolipins / immunology
  • Cerebral Infarction / etiology
  • Cerebral Infarction / virology
  • Child, Preschool
  • Herpesviridae Infections / blood
  • Herpesviridae Infections / complications*
  • Herpesvirus 6, Human / pathogenicity*
  • Humans
  • Magnetic Resonance Angiography / methods
  • Magnetic Resonance Imaging / methods
  • Male
  • Retrospective Studies

Substances

  • Antibodies
  • Cardiolipins