Pasteurized autograft-prosthesis composite for distal femoral osteosarcoma

J Orthop Sci. 2007 Nov;12(6):542-9. doi: 10.1007/s00776-007-1173-7. Epub 2007 Nov 30.

Abstract

Background: We examined the survivorship and functional outcome of the pasteurized autograft-prosthesis composite for distal femoral osteosarcoma. We also evaluated complications including nonunion, loosening, bony resorption, infection, and fracture.

Methods: We retrospectively reviewed 15 distal femoral osteosarcoma patients who underwent reconstructions using pasteurized autograft-prosthesis composite between 1993 and 2003.

Results: No patient required graft removal during a minimum follow-up of 35 months (average 56 months; range 35-78 months). The average Musculoskeletal Tumor Society System (MTSS) functional score was 86%. Nonunion developed in five patients, and three of them subsequently showed loosening of the stem. No patient experienced infection or fracture.

Conclusions: Our data suggest that the pasteurized autograft-prosthesis composite could be an easily accessible alternative for the reconstruction of large skeletal defects in the distal femur because of the satisfactory functional outcome with a low rate of ultimate failure and complications in this study.

MeSH terms

  • Adolescent
  • Adult
  • Bone Neoplasms / diagnosis
  • Bone Neoplasms / surgery*
  • Bone Transplantation / methods*
  • Female
  • Femur*
  • Follow-Up Studies
  • Graft Survival
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Orthopedic Procedures / methods*
  • Osteosarcoma / diagnosis
  • Osteosarcoma / surgery*
  • Prostheses and Implants*
  • Prosthesis Design
  • Retrospective Studies
  • Tibia / transplantation*
  • Time Factors
  • Transplantation, Autologous
  • Treatment Outcome