Vaginal paravaginal repair with an AlloDerm graft: Long-term outcomes

Am J Obstet Gynecol. 2007 Dec;197(6):670.e1-5. doi: 10.1016/j.ajog.2007.08.067.

Abstract

Objective: The aim of this study was to describe the long-term objective and subjective outcomes after vaginal paravaginal repair with AlloDerm graft (LifeCell, Branchburg, NJ).

Study design: Thirty-three women with either recurrent stage II or primary or recurrent stage III-IV anterior vaginal wall prolapse underwent a vaginal paravaginal repair with AlloDerm graft between November 1998 and April 2002. Postoperative follow-up was obtained on an annual basis. Objective failure was defined as a stage II or greater anterior wall defect. Descriptive statistics were performed.

Results: Long-term follow-up was obtained on 24/33 subjects (72.7%). The mean length of follow-up for the 24 women was 52.0 months (range, 18-86 months). Fourteen of the 24 subjects (58.3%) had recurrent stage II prolapse in the anterior compartment, of which only 4 of 14 (28.6%) were symptomatic.

Conclusions: Long-term evaluation of vaginal paravaginal repairs with AlloDerm graft reveals good subjective success, despite a moderate rate of objective failure within the first 24 months.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Biocompatible Materials*
  • Collagen*
  • Female
  • Gynecologic Surgical Procedures / methods*
  • Humans
  • Middle Aged
  • Recurrence
  • Treatment Outcome
  • Uterine Prolapse / surgery*
  • Vagina / surgery*

Substances

  • Alloderm
  • Biocompatible Materials
  • Collagen