Induction of Toll-like receptor 2 and 4 expression on CD4+ and CD8+ T cells in G-CSF-mobilized unrelated peripheral blood stem cell grafts during leukapheresis: impact on patient outcome

Leukemia. 2008 Jul;22(7):1438-40. doi: 10.1038/sj.leu.2405075. Epub 2007 Dec 13.
No abstract available

Publication types

  • Comment
  • Letter

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • CD4-Positive T-Lymphocytes / metabolism*
  • CD8-Positive T-Lymphocytes / metabolism*
  • Female
  • Graft vs Host Disease / etiology*
  • Granulocyte Colony-Stimulating Factor / pharmacology*
  • Hematopoietic Stem Cell Mobilization*
  • Humans
  • Leukapheresis*
  • Male
  • Middle Aged
  • Peripheral Blood Stem Cell Transplantation* / adverse effects
  • Peripheral Blood Stem Cell Transplantation* / mortality
  • Polymorphism, Single Nucleotide
  • Toll-Like Receptor 2 / genetics*
  • Toll-Like Receptor 4 / genetics*

Substances

  • TLR2 protein, human
  • TLR4 protein, human
  • Toll-Like Receptor 2
  • Toll-Like Receptor 4
  • Granulocyte Colony-Stimulating Factor