Specific T-cell response to a Pneumocystis carinii surface glycoprotein (gp120)

J Protozool. 1991 Nov-Dec;38(6):22S-23S.

Abstract

Pneumocystis carinii gp120 can elicit a specific T-cell proliferative response in mice after immunization with a gp120 preparation or with a crude P. carinii homogenate. It can also elicit a proliferative response from SCID mice after recovery from natural infection with P. carinii, implicating this glycoprotein as an important antigen in the host's response to P. carinii infection.

MeSH terms

  • Animals
  • Blotting, Western
  • Fungal Proteins / immunology*
  • Immunization
  • Membrane Glycoproteins / immunology*
  • Mice
  • Mice, Inbred BALB C
  • Mice, SCID
  • Pneumocystis / immunology*
  • T-Lymphocytes / immunology*

Substances

  • Fungal Proteins
  • Membrane Glycoproteins