The radiologic diagnosis of craniosynostosis is made in most instances based on routine skull films, because each suture closure produces characteristic changes. Computed tomography (CT) was originally used only to evaluate the intracranial contents. In the last 5 years changes in morphology at the skull base and in the calvarium have been better demonstrated with three-dimensional CT. This article describes and illustrates the appearance of craniosynostosis on skull radiographs and CT.