A long-term durable remission with high-dose therapy and autologous stem cell transplant for stage IVB HIV-associated Hodgkins disease

AIDS. 2008 Feb 19;22(4):539-40. doi: 10.1097/QAD.0b013e3282f0e3e5.

Abstract

A 44-year-old man with relapsed HIV-associated stage IV nodular sclerosing Hodgkin's disease underwent high-dose therapy with autologous stem cell transplantation. The transplant was uncomplicated and the patient remains in complete remission at 59 months. Autologous stem cell transplantation is safe in HIV patients and can achieve long-term durable remissions in Hodgkin's disease.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Antineoplastic Combined Chemotherapy Protocols / administration & dosage
  • Antiretroviral Therapy, Highly Active*
  • Cyclophosphamide / administration & dosage
  • Cytarabine / administration & dosage
  • Etoposide / administration & dosage
  • Hematopoietic Stem Cell Mobilization / methods*
  • Hematopoietic Stem Cell Transplantation / methods*
  • Hodgkin Disease / therapy*
  • Humans
  • Lomustine / administration & dosage
  • Lymphoma, AIDS-Related / therapy*
  • Male
  • Remission Induction / methods
  • Transplantation, Autologous

Substances

  • Cytarabine
  • Etoposide
  • Lomustine
  • Cyclophosphamide