Abstract
The authors discuss evidence suggesting that embryonic signaling pathways involved in epithelium/mesenchymal communication and epithelial cell plasticity may be aberrantly switched on in idiopathic pulmonary fibrosis.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Cell Proliferation
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Epithelial Cells / pathology
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Fibroblasts / pathology
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Genes, Developmental
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Humans
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Lung / embryology
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Lung / metabolism
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Lung / pathology
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Mesoderm / pathology
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Morphogenesis* / genetics
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Pulmonary Fibrosis / genetics
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Pulmonary Fibrosis / pathology*
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Pulmonary Fibrosis / therapy
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Signal Transduction
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Transcription, Genetic