Does antisense make sense of AID targeting?

Proc Natl Acad Sci U S A. 2008 Mar 11;105(10):3661-2. doi: 10.1073/pnas.0800935105. Epub 2008 Mar 5.
No abstract available

Publication types

  • Comment
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cytidine Deaminase / metabolism*
  • Genes, Immunoglobulin Heavy Chain / genetics
  • Immunoglobulin Class Switching / genetics
  • Immunoglobulin Heavy Chains / genetics
  • Immunoglobulin Variable Region / genetics
  • Mice
  • RNA, Antisense / genetics*
  • Somatic Hypermutation, Immunoglobulin
  • VDJ Exons / genetics

Substances

  • Immunoglobulin Heavy Chains
  • Immunoglobulin Variable Region
  • RNA, Antisense
  • AICDA (activation-induced cytidine deaminase)
  • Cytidine Deaminase