Patch size, shape and orientation affect geometrical outcomes of surgical anterior ventricular restoration

J Cardiovasc Med (Hagerstown). 2008 Apr;9(4):389-95. doi: 10.2459/JCM.0b013e3282eee951.

Abstract

Objectives: To verify whether the use of a small, oval-shaped patch limits the trend toward re-dilatation compared to endoventricular circular patch plasty and leads to different geometrical and functional results in surgical anterior restoration.

Methods: Thirty-seven patients with ischemic cardiomyopathy after anterior myocardial infarction end-systolic volume index of > or =45 ml/m2, ejection fraction of < or =35%, and no combined mitral procedures, underwent surgical anterior ventricular restoration between January 2000 and April 2003: 18 patients (group 1) were operated on using the endoventricular circular patch plasty technique (mean patch area 9.6 cm2) and 19 patients (group 2) received a small, obliquely oriented, oval-shaped patch (mean patch area 6.2 cm2). Ten geometrical parameters were studied preoperatively and at least 6 and 12 months after surgery. Data were analyzed using repeated-measures ANOVA, chi2, paired and unpaired Student's t-test, and binary logistic regression.

Results: Group 1 showed a worsening over time in systolic and diastolic longitudinal length, end-diastolic volume (P < 0.001), end-diastolic volume index (P = 0.006), end-systolic volume (P = 0.005), and end-systolic volume index (P = 0.03). Group 2 showed an improvement in percentage of akinesia and wall motion score index (P < 0.001) and a worsening only in end-systolic diameter (P = 0.03) and end-diastolic volume (P = 0.04). At 12-month follow-up, ANOVA revealed that the oval patch positively influenced end-diastolic volume (P = 0.03), end-systolic volume (P = 0.03), and end-systolic volume index (P = 0.05), and group 2 had a significantly higher number of patients with an end-systolic volume index of <45 ml/m2 (P = 0.01).

Conclusion: The use of a small, narrow, obliquely oriented, oval patch may help to prevent adverse ventricular remodeling over time.

MeSH terms

  • Aged
  • Analysis of Variance
  • Animals
  • Bioprosthesis*
  • Cardiac Surgical Procedures / methods
  • Cattle
  • Chi-Square Distribution
  • Coronary Artery Bypass
  • Echocardiography
  • Female
  • Heart Ventricles / surgery*
  • Humans
  • Logistic Models
  • Male
  • Middle Aged
  • Myocardial Infarction / complications*
  • Myocardial Ischemia / diagnostic imaging
  • Myocardial Ischemia / etiology
  • Myocardial Ischemia / physiopathology
  • Myocardial Ischemia / surgery*
  • Pilot Projects
  • Treatment Outcome
  • Ventricular Remodeling