Treatment of a basilar artery occlusion with intra-arterial thrombolysis in a 3-year-old girl

Neurocrit Care. 2008;9(3):357-60. doi: 10.1007/s12028-008-9086-7.

Abstract

Introduction: Posterior circulation stroke attributable to basilar artery thrombosis is a rare entity and is difficult to diagnose in young children. Given the high rate of disability and mortality associated with the condition, endovascular revascularization may be a potential treatment strategy.

Case: We describe a 3-year-old girl who presented with a decline in consciousness associated with tonic and clonic movements of her extremities thought to be secondary to a seizure. She was found to have a basilar artery occlusion 18 h from last known to be normal and was successfully treated with intra-arterial alteplase. At 6 month follow up the child has made substantial improvements and is in preschool with difficulties with ambulating longer distances.

Conclusion: We report the youngest patient in the literature to date who was treated with intra-arterial thrombolysis for an acute basilar artery occlusion.

Publication types

  • Case Reports

MeSH terms

  • Catheterization
  • Child, Preschool
  • Female
  • Fibrinolytic Agents / administration & dosage*
  • Humans
  • Infusions, Intra-Arterial
  • Thrombolytic Therapy*
  • Thrombosis / drug therapy*
  • Tissue Plasminogen Activator / administration & dosage*
  • Vertebrobasilar Insufficiency / drug therapy*

Substances

  • Fibrinolytic Agents
  • Tissue Plasminogen Activator