The effects of a training program consisting of weight lifting combined with plyometric exercises on kicking performance, myosin heavy-chain composition (vastus lateralis), physical fitness, and body composition (using dual-energy X-ray absorptiometry (DXA)) was examined in 37 male physical education students divided randomly into a training group (TG: 16 subjects) and a control group (CG: 21 subjects). The TG followed 6 weeks of combined weight lifting and plyometric exercises. In all subjects, tests were performed to measure their maximal angular speed of the knee during in-step kicks on a stationary ball. Additional tests for muscle power (vertical jump), running speed (30 m running test), anaerobic capacity (Wingate and 300 m running tests), and aerobic power (20 m shuttle run tests) were also performed. Training resulted in muscle hypertrophy (+4.3%), increased peak angular velocity of the knee during kicking (+13.6%), increased percentage of myosin heavy-chain (MHC) type IIa (+8.4%), increased 1 repetition maximum (1 RM) of inclined leg press (ILP) (+61.4%), leg extension (LE) (+20.2%), leg curl (+15.9%), and half squat (HQ) (+45.1%), and enhanced performance in vertical jump (all p < or = 0.05). In contrast, MHC type I was reduced (-5.2%, p < or = 0.05) after training. In the control group, these variables remained unchanged. In conclusion, 6 weeks of strength training combining weight lifting and plyometric exercises results in significant improvement of kicking performance, as well as other physical capacities related to success in football (soccer).