Porin new light onto chromatin and nuclear organization

Genome Biol. 2008;9(5):222. doi: 10.1186/gb-2008-9-5-222. Epub 2008 May 16.

Abstract

A recent report identifies sites in the human genome that can associate with nucleoporin 93, a subunit of the nuclear pore complex. These associations are modulated by levels of global histone acetylation and highlight the dynamic nature of chromatin organization in the nucleus.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Cell Nucleus / chemistry*
  • Chromatin / chemistry*
  • Histone Deacetylases / metabolism
  • Humans
  • Nuclear Pore Complex Proteins / metabolism
  • Porins / metabolism*

Substances

  • Chromatin
  • Nuclear Pore Complex Proteins
  • Porins
  • Histone Deacetylases