Chronic cystic lesion of the sacrum: characterisation with diffusion-weighted MR imaging

Radiol Med. 2008 Aug;113(5):739-46. doi: 10.1007/s11547-008-0283-4. Epub 2008 Jun 3.
[Article in English, Italian]

Abstract

Purpose: Sacral bone remodelling with abnormal dilatation of intervertebral foramina is usually associated with Tarlov cysts but can be caused by slow-growth lesions, which also may present cerebrospinal-fluid (CSF)-like signal or density. We describe three patients with a similar history of lower back pain presenting CSF-like density/signal lesions with extensive sacral bone remodelling who were affected by a Tarlov cyst, an epidermoid cyst and a giant neurofibroma, respectively.

Materials and methods: Magnetic resonance imaging (MRI) studies were performed with 1.0-T magnet; axial and sagittal pre- and postcontrast T1-and T2-weighted images were obtained. Moreover, axial and sagittal diffusion-weighted (DWI) echoplanar images were produced, and corresponding apparent diffusion coefficient (ADC) values were calculated. ADC values were measured within the lesions on axial images.

Results: All lesions presented a CSF-like signal on conventional MRI. The Tarlov cyst was hypointense on DWI with high ADC values (2,793 s/mm(2)+/-137). The epidermoid cyst proved to be markedly hyperintense on DWI, with reduced ADC values (855 s/mm(2)+/-109). The neurofibroma was isointense on DWI, with ADC values not compatible with CSF (1,467 s/mm(2)+/-130).

Conclusions: DWI and ADC values seem to be able to clearly differentiate Tarlov cysts from slow-growth lesions, allowing for adequate treatment.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Diffusion Magnetic Resonance Imaging*
  • Epidermal Cyst / diagnosis*
  • Epidermal Cyst / diagnostic imaging
  • Female
  • Humans
  • Middle Aged
  • Neurofibroma / diagnosis*
  • Neurofibroma / diagnostic imaging
  • Sacrum / diagnostic imaging
  • Sacrum / pathology*
  • Spinal Neoplasms / diagnosis*
  • Spinal Neoplasms / diagnostic imaging
  • Tarlov Cysts / diagnosis*
  • Tarlov Cysts / diagnostic imaging
  • Tomography, X-Ray Computed