Availability of the epinephrine autoinjector at school in children with peanut allergy

Ann Allergy Asthma Immunol. 2008 Jun;100(6):570-5. doi: 10.1016/S1081-1206(10)60056-7.

Abstract

Background: Peanut allergy accounts for most severe food-related allergic reactions, and accidental exposures are frequent. Delayed administration of epinephrine and the allergic individual's failure to personally carry epinephrine contribute to fatal outcomes.

Objectives: To describe epinephrine autoinjector availability at school and to determine factors that might affect autoinjector availability in children allergic to peanut.

Methods: Two hundred seventy-one children with peanut allergy living in Quebec were queried about their autoinjector. Logistic regression models were used to select factors associated with device availability.

Results: Four of 271 children diagnosed as having peanut allergy were not prescribed autoinjectors. Forty-eight percent of the children did not carry the autoinjector with them at school. In 78.0% of those, the autoinjector was located in the nurse's or another school office, which was staffed by a full-time nurse only in 18.5%. Of all the respondents, those administered epinephrine for a previous reaction (odds ratio [OR], 2.7; 95% confidence interval [CI], 1.3-5.7), older children (OR, 1.1; 95% CI, 1.0-1.2), and those living only with their mother (OR, 3.4; 95% CI, 1.0-11.0) were more likely to carry the autoinjector with them at school. Of children 7 years or older, those who experienced a severe reaction were more likely to carry their autoinjector (OR, 3.3; 95% CI, 1.4-8.1).

Conclusions: Almost 50% of children allergic to peanut might experience a delay in anaphylaxis treatment due to limited access to their device. More education is required regarding the importance of a readily available autoinjector.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Age Factors
  • Bronchodilator Agents / administration & dosage
  • Bronchodilator Agents / therapeutic use
  • Child
  • Child, Preschool
  • Epinephrine / administration & dosage*
  • Epinephrine / therapeutic use
  • Female
  • Humans
  • Injections, Intramuscular / instrumentation
  • Male
  • Odds Ratio
  • Patient Compliance / statistics & numerical data*
  • Patient Education as Topic
  • Peanut Hypersensitivity / drug therapy*
  • Quebec
  • Single-Parent Family
  • Surveys and Questionnaires

Substances

  • Bronchodilator Agents
  • Epinephrine