Comparison of multidetector CT angiography and MR imaging of cervical artery dissection

AJNR Am J Neuroradiol. 2008 Oct;29(9):1753-60. doi: 10.3174/ajnr.A1189. Epub 2008 Jul 17.

Abstract

Background and purpose: Conventional angiography has been historically considered the gold standard for the diagnosis of cervical artery dissection, but MR imaging/MR angiography (MRA) and CT/CT angiography (CTA) are commonly used noninvasive alternatives. The goal of this study was to compare the ability of multidetector CT/CTA and MR imaging/MRA to detect common imaging findings of dissection.

Materials and methods: Patients in the data base of our Stroke Center between 2003 and 2007 with dissections who had CT/CTA and MR imaging/MRA on initial work-up were reviewed retrospectively. Two neuroradiologists evaluated the images for associated findings of dissection, including acute ischemic stroke, luminal narrowing, vessel irregularity, wall thickening/hematoma, pseudoaneurysm, and intimal flap. The readers also subjectively rated each vessel on the basis of whether the imaging findings were more clearly displayed with CT/CTA or MR imaging/MRA or were equally apparent.

Results: Eighteen patients with 25 dissected vessels (15 internal carotid arteries [ICA] and 10 vertebral arteries [VA]) met the inclusion criteria. CT/CTA identified more intimal flaps, pseudoaneurysms, and high-grade stenoses than MR imaging/MRA. CT/CTA was preferred for diagnosis in 13 vessels (5 ICA, 8 VA), whereas MR imaging/MRA was preferred in 1 vessel (ICA). The 2 techniques were deemed equal in the remaining 11 vessels (9 ICA, 2 VA). A significant preference for CT/CTA was noted for VA dissections (P < .05), but not for ICA dissections.

Conclusion: Multidetector CT/CTA visualized more features of cervical artery dissection than MR imaging/MRA. CT/CTA was subjectively favored for vertebral dissection, whereas there was no technique preference for ICA dissection. In many cases, MR imaging/MRA provided complementary or confirmatory information, particularly given its better depiction of ischemic complications.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Aneurysm, False / diagnosis
  • Angiography*
  • Carotid Artery, Internal / pathology
  • Carotid Artery, Internal, Dissection / diagnosis*
  • Cerebral Infarction / diagnosis
  • Cone-Beam Computed Tomography*
  • Contrast Media / administration & dosage
  • Female
  • Humans
  • Image Processing, Computer-Assisted*
  • Magnetic Resonance Angiography*
  • Male
  • Middle Aged
  • Sensitivity and Specificity
  • Tomography, Spiral Computed*
  • Tomography, X-Ray Computed*
  • Vertebral Artery / pathology
  • Vertebral Artery Dissection / diagnosis*

Substances

  • Contrast Media