Umbilical cord ulceration after prenatal diagnosis of duodenal atresia with interstitial deletion of chromosome 13q: a case report

Fetal Diagn Ther. 2008;24(2):115-8. doi: 10.1159/000142140. Epub 2008 Jul 17.

Abstract

Umbilical cord ulceration complicated by massive local hemorrhage may be a lethal event in the fetus, and this ulceration has been reported to be associated with upper intestinal atresia. The diagnosis of umbilical cord bleeding is difficult. We present a case of umbilical cord ulceration, hemorrhage, and duodenal atresia which had, in addition, an interstitial deletion of chromosome 13q. A female infant weighing 1,691 g was delivered by cesarean section at 34 weeks of gestation and had resuscitation and laparotomy. Just before the cesarean section, ultrasonography showed a 'double bubble' sign and a linear shadow, suggesting fibrin in the amniotic cavity. This finding may help in the diagnosis of bleeding from the cord.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Cesarean Section
  • Chromosome Deletion*
  • Chromosomes, Human, Pair 13*
  • Duodenal Obstruction / complications
  • Duodenal Obstruction / diagnostic imaging*
  • Duodenal Obstruction / genetics
  • Duodenal Obstruction / pathology
  • Female
  • Hemorrhage / diagnostic imaging
  • Hemorrhage / etiology*
  • Humans
  • Infant, Low Birth Weight
  • Infant, Newborn
  • Intestinal Atresia / complications
  • Intestinal Atresia / diagnostic imaging*
  • Intestinal Atresia / genetics
  • Intestinal Atresia / pathology
  • Karyotyping
  • Pregnancy
  • Tomography, X-Ray Computed
  • Ulcer / diagnostic imaging
  • Ulcer / etiology*
  • Ultrasonography, Prenatal*
  • Umbilical Cord / diagnostic imaging*