Serological and molecular survey of Rickettsial infection in cattle and sika deer in a pastureland in Hidaka District, Hokkaido, Japan

Jpn J Infect Dis. 2008 Jul;61(4):315-7.

Abstract

Rickettsial infection of cattle and sika deer from a pastureland in Hidaka District, Hokkaido, Japan was examined by serological and molecular methods. Serum samples from 8 of 83 (9.6%) cattle reacted with Rickettsia helvetica antigens in an IFA test, with titers ranging from 1:160 to 1:640, while serum samples from 15 of 22 (68.2%) deer were positive for R. helvetica, with titers ranging from 1:80 to 1:640. In a genus-specific nested PCR based on gltA, no cattle were positive for Rickettsia, while 14 of 22 (63.3%) samples obtained from deer tested positive. Sequence analysis revealed that positive samples from sika deer showed 100% nucleotide sequence identity with the known sequence of Rickettsia asiatica.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antibodies, Bacterial / blood*
  • Antigens, Bacterial / blood
  • Cattle
  • Cattle Diseases / epidemiology
  • Cattle Diseases / microbiology*
  • DNA, Bacterial / analysis
  • DNA, Bacterial / isolation & purification
  • Deer
  • Japan / epidemiology
  • Polymerase Chain Reaction
  • Rickettsia Infections / epidemiology
  • Rickettsia Infections / microbiology
  • Rickettsia Infections / veterinary*
  • Rickettsia* / classification
  • Rickettsia* / genetics
  • Rickettsia* / immunology
  • Rickettsia* / isolation & purification

Substances

  • Antibodies, Bacterial
  • Antigens, Bacterial
  • DNA, Bacterial