Nutritional management of patients with acute pancreatitis: a Dutch observational multicentre study

Aliment Pharmacol Ther. 2008 Nov 1;28(9):1159-65. doi: 10.1111/j.1365-2036.2008.03814.x. Epub 2008 Jul 24.

Abstract

Background: Following a nil per os (NPO) regimen, most patients with acute pancreatitis (AP) can resume normal oral intake within 1 week. If not tolerated, it is recommended to initiate artificial feeding, preferably by the enteral route.

Aim: To evaluate the nutritional management of patients with AP in a Dutch cohort (EARL study).

Methods: Observational study in 18 hospitals. Total days of NPO, tube feeding (TF) with/without oral feeding, total parenteral nutrition (TPN) and total starvation time were analysed.

Results: In mild AP, a majority of cases (80.7%, 117/145) were managed with an NPO regimen only. Twenty-seven patients (18.6%) with mild AP additionally received TF; one received TPN. Of those with severe AP, more than half of the patients (56.2%, nine of 16) were treated with TF besides an NPO regimen; four received TPN. TF was delivered preferably via the jejunal route. The median period of total starvation was 2 days for both mild and severe AP. Only 5.5% (nine of 164) of patients had a prolonged starvation time of more than 5 days.

Conclusions: The total time of starvation was limited in a majority of patients admitted for AP. According to international guidelines, additional nutritional interventions were quickly undertaken with enteral feeding via the jejunum as the preferred route.

Publication types

  • Multicenter Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acute Disease
  • Cohort Studies
  • Enteral Nutrition / methods*
  • Female
  • Humans
  • Length of Stay
  • Male
  • Netherlands
  • Pancreatitis / therapy*
  • Parenteral Nutrition / methods*
  • Prospective Studies
  • Starvation
  • Time Factors
  • Treatment Outcome