Rac guanosine triphosphatases represent a potential target in AML

Leukemia. 2008 Sep;22(9):1803-6. doi: 10.1038/leu.2008.196. Epub 2008 Jul 31.
No abstract available

Publication types

  • Letter
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aminoquinolines
  • Animals
  • Cell Cycle / drug effects
  • Cell Line, Tumor
  • Cell Proliferation / drug effects
  • Cell Survival / drug effects
  • Drug Delivery Systems
  • Drug Screening Assays, Antitumor
  • Enzyme Inhibitors / pharmacology
  • Enzyme Inhibitors / therapeutic use
  • Humans
  • Leukemia, Myeloid, Acute / drug therapy*
  • Mice
  • Pyrimidines
  • Survival Rate
  • Transplantation, Heterologous
  • rac GTP-Binding Proteins / antagonists & inhibitors*

Substances

  • Aminoquinolines
  • Enzyme Inhibitors
  • NSC 23766
  • Pyrimidines
  • rac GTP-Binding Proteins