Novel therapeutic targets in neurodegenerative diseases: lessons from amyotrophic lateral sclerosis

Curr Neurol Neurosci Rep. 2008 Sep;8(5):353-5. doi: 10.1007/s11910-008-0054-6.
No abstract available

Publication types

  • Review

MeSH terms

  • Amyotrophic Lateral Sclerosis / drug therapy*
  • Amyotrophic Lateral Sclerosis / pathology
  • Animals
  • Disease Models, Animal
  • Drug Delivery Systems*
  • Drug Evaluation, Preclinical
  • Humans
  • Mice
  • Mice, Transgenic
  • Microglia / physiology
  • Motor Neurons / pathology
  • Nerve Tissue Proteins / metabolism
  • Neurodegenerative Diseases / drug therapy*
  • Neurodegenerative Diseases / pathology
  • Oligonucleotides, Antisense / therapeutic use
  • Oxidation-Reduction
  • Protein Folding
  • Superoxide Dismutase / genetics
  • Superoxide Dismutase / physiology
  • Superoxide Dismutase-1

Substances

  • Nerve Tissue Proteins
  • Oligonucleotides, Antisense
  • SOD1 protein, human
  • Sod1 protein, mouse
  • Superoxide Dismutase
  • Superoxide Dismutase-1