The use of intra-coronary optical coherence tomography for the assessment of sirolimus-eluting stent fracture

Int J Cardiol. 2009 Jul 24;136(1):e16-20. doi: 10.1016/j.ijcard.2008.04.076. Epub 2008 Aug 23.

Abstract

Drug-eluting stents (DES) have made a tremendous impact on the practice of percutaneous coronary intervention. Recently however, long-term DES failures have become a focal point, particularly with restenosis and thrombosis. An uncommon, yet important cause of DES failure is stent fracture. Of the two established first generation DES, the sirolimus-eluting stent (SES) has been particularly linked to cases of stent fracture, likely as a result of its closed cell design compared with other DES employing an open cell system. We present 2 cases of SES fracture confirmed using high-resolution intravascular optical coherence tomography giving unique insights into the in-vivo appearance of this complication.

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Aged
  • Coronary Restenosis / diagnostic imaging*
  • Coronary Restenosis / etiology
  • Coronary Vessels / diagnostic imaging*
  • Drug-Eluting Stents / adverse effects*
  • Humans
  • Male
  • Middle Aged
  • Prosthesis Failure
  • Sirolimus / administration & dosage*
  • Tomography, Optical Coherence / methods*
  • Tomography, Optical Coherence / statistics & numerical data
  • Ultrasonography

Substances

  • Sirolimus