Excessive calcium ingestion leading to milk-alkali syndrome

Ann Clin Biochem. 2008 Sep;45(Pt 5):527-9. doi: 10.1258/acb.2008.008006.

Abstract

This report describes the presentation and clinical course of a 40-year-old woman who had an emergency admission for eclampsia. During routine investigations, she was found to have profound hypercalcaemia, the cause of which was identified as milk-alkali syndrome, caused by self-medication with antacid tablets for dyspepsia. Treatment with aggressive rehydration, bisphosphonates and discontinuation of antacid tablets restored normocalcaemia. The patient made a full recovery with no long-term side-effects. Her male infant was safely delivered with no deleterious effects of exposure to high calcium concentrations in utero.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antacids / adverse effects*
  • Calcium / adverse effects*
  • Diphosphonates / pharmacology
  • Dyspepsia / complications
  • Dyspepsia / drug therapy
  • Female
  • Humans
  • Hypercalcemia / chemically induced*
  • Hypercalcemia / diagnosis*
  • Hypercalcemia / therapy
  • Male
  • Pre-Eclampsia / diagnosis
  • Pregnancy
  • Pregnancy Complications
  • Pregnancy Outcome
  • Time Factors

Substances

  • Antacids
  • Diphosphonates
  • Calcium