Atherosclerotic and pleural calcifications are related among asbestos-exposed workers

Eur J Cardiovasc Prev Rehabil. 2008 Oct;15(5):599-601. doi: 10.1097/HJR.0b013e328309a224.

Abstract

Methods: We studied the relationship between calcified chest atherosclerosis and pleural plaques among 505 construction workers with computed tomography. The extent and thickness of pleural plaques and the score of visceral pleural thickening were estimated, as was calcification of both pleural disease and chest atherosclerosis.

Results: Adjusted for age, BMI, smoking, and asbestos exposure, pleural calcification was associated with calcification in coronary arteries (P<0.001) and in the aorta (P<0.001).

Conclusion: These associations may be due to susceptibility factors common to both conditions. Calcification in pleural plaques may be a hint of atherosclerosis at least among asbestos-exposed people.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Asbestos / adverse effects*
  • Asbestosis / diagnostic imaging
  • Asbestosis / etiology*
  • Atherosclerosis / diagnostic imaging
  • Atherosclerosis / etiology*
  • Calcinosis / diagnostic imaging
  • Calcinosis / etiology*
  • Construction Materials / adverse effects*
  • Humans
  • Male
  • Middle Aged
  • Occupational Diseases / diagnostic imaging
  • Occupational Diseases / etiology*
  • Occupational Exposure*
  • Pleural Diseases / diagnostic imaging
  • Pleural Diseases / etiology*
  • Retrospective Studies
  • Tomography, X-Ray Computed

Substances

  • Asbestos