alpha-Naphthylaminopropan-2-ol Derivatives as BACE1 Inhibitors

ChemMedChem. 2008 Oct;3(10):1530-4. doi: 10.1002/cmdc.200800162.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • 1-Naphthylamine / analogs & derivatives*
  • 1-Naphthylamine / chemistry
  • Amyloid Precursor Protein Secretases / antagonists & inhibitors*
  • Aspartic Acid Endopeptidases / antagonists & inhibitors*
  • Carbazoles / chemistry*
  • Fluorescent Dyes / chemistry
  • Humans
  • Inhibitory Concentration 50
  • Protease Inhibitors / chemistry*
  • Protease Inhibitors / pharmacology
  • Structure-Activity Relationship

Substances

  • Carbazoles
  • Fluorescent Dyes
  • Protease Inhibitors
  • 1-Naphthylamine
  • Amyloid Precursor Protein Secretases
  • Aspartic Acid Endopeptidases
  • BACE1 protein, human