Prospective study of fecal colonization by extended-spectrum-beta-lactamase-producing Escherichia coli in neutropenic patients with cancer

Antimicrob Agents Chemother. 2008 Nov;52(11):4187-90. doi: 10.1128/AAC.00367-08. Epub 2008 Sep 22.

Abstract

Fecal colonization by extended-spectrum-beta-lactamase-producing Escherichia coli in 912 stool samples collected from 154 neutropenic patients with cancer, hospitalized at two teaching institutions, was prospectively studied. Forty-nine (31.8%) patients were colonized, 22 of them at hospital admission. Most strains were clonally unrelated and carried a CTX-M-9 group enzyme.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Drug Resistance, Bacterial
  • Escherichia coli / drug effects
  • Escherichia coli / enzymology*
  • Escherichia coli / isolation & purification
  • Escherichia coli / pathogenicity
  • Escherichia coli Infections / complications
  • Escherichia coli Infections / drug therapy
  • Escherichia coli Infections / microbiology
  • Feces / microbiology
  • Humans
  • Neoplasms / complications
  • Neoplasms / microbiology*
  • Neutropenia / complications
  • Neutropenia / microbiology
  • Prospective Studies
  • beta-Lactam Resistance
  • beta-Lactamases / biosynthesis*

Substances

  • beta-Lactamases