Three-class-resistant human immunodeficiency virus type 1 variant in a drug-naive heterosexual couple

J Clin Microbiol. 2008 Nov;46(11):3856-9. doi: 10.1128/JCM.01122-08. Epub 2008 Sep 24.

Abstract

Combination antiretroviral treatment was initiated in a heterosexual couple newly diagnosed with human immunodeficiency virus type 1 infection. Multiple genotypic drug resistance testing following early rebound of viral load revealed that the same three-class-resistant human immunodeficiency virus type 1 strain had been present in both patients since before initiation of treatment.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-HIV Agents / therapeutic use*
  • Drug Resistance, Viral*
  • Family Characteristics
  • Female
  • HIV Infections / drug therapy*
  • HIV Infections / virology*
  • HIV-1 / drug effects*
  • HIV-1 / genetics
  • HIV-1 / isolation & purification*
  • Heterosexuality
  • Humans
  • Male
  • Middle Aged
  • RNA, Viral / genetics*
  • Viral Load

Substances

  • Anti-HIV Agents
  • RNA, Viral