Molecular characterization of biologically diverse envelope variants of human immunodeficiency virus type 1 derived from an individual

J Virol. 1991 Oct;65(10):5574-8. doi: 10.1128/JVI.65.10.5574-5578.1991.

Abstract

The envelope genes of six viruses derived from a single sampling from an individual chronically infected with human immunodeficiency virus type 1 (RJS-4) have been analyzed. Here we present the nucleotide and predicted amino acid sequences of these variants and show a correlation between biological properties and disturbance of the envelope reading frame.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acquired Immunodeficiency Syndrome / blood
  • Acquired Immunodeficiency Syndrome / microbiology
  • Amino Acid Sequence
  • Cell Line
  • Chromosome Deletion
  • Gene Library
  • Gene Products, rev / genetics*
  • Gene Products, tat / genetics*
  • Genetic Variation*
  • HIV-1 / genetics*
  • HIV-1 / isolation & purification
  • Humans
  • Molecular Sequence Data
  • Restriction Mapping
  • Viral Envelope Proteins / genetics*
  • rev Gene Products, Human Immunodeficiency Virus
  • tat Gene Products, Human Immunodeficiency Virus

Substances

  • Gene Products, rev
  • Gene Products, tat
  • Viral Envelope Proteins
  • rev Gene Products, Human Immunodeficiency Virus
  • tat Gene Products, Human Immunodeficiency Virus