A multicentric study on sensitivity and specificity of a new in vitro test for measurement of IgE antibodies

Ann Allergy. 1991 Sep;67(3):365-70.

Abstract

The sensitivity and specificity of the Pharmacia CAP System, a new in vitro assay for measuring IgE antibodies, were evaluated in a multicentric study on 286 allergic patients and 243 normal subjects. Sensitivity was 95.5%, with results significantly better than RAST for some allergens, and specificity was excellent, 98.1%.

Publication types

  • Clinical Trial
  • Multicenter Study

MeSH terms

  • Adolescent
  • Adult
  • Antibodies, Anti-Idiotypic / analysis*
  • Antibody Specificity
  • Humans
  • Immunoglobulin E / analysis
  • Immunoglobulin E / immunology*
  • Methods
  • Middle Aged
  • Radioallergosorbent Test
  • Sensitivity and Specificity

Substances

  • Antibodies, Anti-Idiotypic
  • anti-IgE antibodies
  • Immunoglobulin E