Low frequency of GB virus C viremia in a cohort of HIV-1-infected elite suppressors

AIDS. 2008 Nov 12;22(17):2398-400. doi: 10.1097/QAD.0b013e328316c3fb.

Abstract

The persistence of GB virus C viremia in patients with chronic HIV-1 infection has been associated with increased survival. Elite suppressors are untreated HIV-1-infected patients who maintain viral loads of below 50 copies/ml. This study found that the frequency of GB virus C viremia in elite suppressors and chronically infected patients with progressive disease was not significantly different. Thus, GB virus C does not appear to explain the nonprogressive course seen in this cohort of elite suppressors.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • AIDS-Related Opportunistic Infections / complications*
  • AIDS-Related Opportunistic Infections / virology
  • Animals
  • CD4 Lymphocyte Count
  • Flaviviridae Infections* / drug therapy
  • GB virus C* / genetics
  • GB virus C* / isolation & purification
  • HIV Infections / complications*
  • HIV Infections / drug therapy
  • HIV-1 / genetics*
  • Hepatitis, Viral, Human / drug therapy
  • Humans
  • Viral Load
  • Viremia / complications
  • Viremia / drug therapy