Brain network analysis from high-resolution EEG recordings by the application of theoretical graph indexes

IEEE Trans Neural Syst Rehabil Eng. 2008 Oct;16(5):442-52. doi: 10.1109/TNSRE.2008.2006196.

Abstract

The extraction of the salient characteristics from brain connectivity patterns is an open challenging topic since often the estimated cerebral networks have a relative large size and complex structure. Since a graph is a mathematical representation of a network, which is essentially reduced to nodes and connections between them, the use of a theoretical graph approach would extract significant information from the functional brain networks estimated through different neuroimaging techniques. The present work intends to support the development of the "brain network analysis:" a mathematical tool consisting in a body of indexes based on the graph theory able to improve the comprehension of the complex interactions within the brain. In the present work, we applied for demonstrative purpose some graph indexes to the time-varying networks estimated from a set of high-resolution EEG data in a group of healthy subjects during the performance of a motor task. The comparison with a random benchmark allowed extracting the significant properties of the estimated networks in the representative Alpha (7-12 Hz) band. Altogether, our findings aim at proving how the brain network analysis could reveal important information about the time-frequency dynamics of the functional cortical networks.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms*
  • Brain Mapping / methods*
  • Electroencephalography / methods*
  • Evoked Potentials, Motor / physiology*
  • Humans
  • Motor Cortex / physiology*
  • Nerve Net / physiology*
  • Neural Pathways / physiology*
  • Sensitivity and Specificity