Does uric acid provide information about maternal condition and fetal outcome in pregnant women with hypertension?

Hypertens Pregnancy. 2008;27(4):413-20. doi: 10.1080/10641950801955709.

Abstract

Objective: To evaluate associations between maternal serum uric acid (UA) levels, maternal status, and fetal outcome.

Methods: Maternal UA, urinary protein-creatinine ratio (P/C), blood pressure (BP), gestational age at delivery, and birth weight were evaluated in hypertensive pregnant women (n = 58). These were divided into two groups: high UA (> or =357 micromol/L) or normal UA (<357 micromol/L).

Results: Maternal diastolic BP and P/C ratio were higher in pregnant women with elevated UA levels. Systolic BP, gestational age and birth weight were not significantly different.

Conclusion: UA equal or above 357 micromol/L in pregnant hypertensive women was associated with proteinuria and diastolic BP, but not with fetal outcome.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Birth Weight*
  • Blood Pressure*
  • Creatinine / urine
  • Female
  • Gestational Age
  • Humans
  • Hypertension, Pregnancy-Induced / blood*
  • Hypertension, Pregnancy-Induced / physiopathology
  • Hypertension, Pregnancy-Induced / urine
  • Infant, Newborn
  • Infant, Premature
  • Pregnancy
  • Premature Birth / blood
  • Premature Birth / urine
  • Proteinuria / urine*
  • Uric Acid / blood*
  • Young Adult

Substances

  • Uric Acid
  • Creatinine