Severe hyperbilirubinemia in a glucose-6-phosphate dehydrogenase-deficient preterm neonate: could prematurity be the main responsible factor?

Fetal Diagn Ther. 2008;24(4):440-3. doi: 10.1159/000174571. Epub 2008 Nov 20.

Abstract

We report on a premature infant with glucose-6-phosphate dehydrogenase deficiency and severe hyperbilirubinemia. In this patient, all known potential hemolytic agents were excluded and no findings of hemolysis were observed. The crucial role of prematurity in the pathogenesis of this type of jaundice is discussed.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anemia, Hemolytic, Congenital / etiology
  • Anemia, Hemolytic, Congenital / genetics
  • Anemia, Hemolytic, Congenital / metabolism
  • Bilirubin / blood
  • Female
  • Glucosephosphate Dehydrogenase Deficiency / complications*
  • Glucosephosphate Dehydrogenase Deficiency / genetics*
  • Glucosephosphate Dehydrogenase Deficiency / metabolism
  • Hematocrit
  • Humans
  • Hyperbilirubinemia, Neonatal / etiology*
  • Hyperbilirubinemia, Neonatal / genetics*
  • Hyperbilirubinemia, Neonatal / metabolism
  • Infant, Newborn
  • Infant, Premature*
  • Male
  • Pregnancy
  • Severity of Illness Index
  • Triplets

Substances

  • Bilirubin