Risk factors in community-acquired/onset urinary tract infections due to extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae

J Chemother. 2008 Oct;20(5):581-5. doi: 10.1179/joc.2008.20.5.581.

Abstract

We investigated the risk factors for community acquired/onset urinary tract infections due to extended spectrum beta-lactamase (ESBL)-positive Escherichia coli or Klebsiella pneumoniae in 62 patients who were followed-up from August 1, 2003 to September 1, 2006. Sixty patients with community-acquired urinary tract infections caused by ESBL-negative E. coli or K. pneumoniae who were followed-up during the same dates were included as a control group. Age (> or =65 or <65 years old), sex, bladder cancer, benign prostate hypertrophy (BPH), prostate cancer, urolithiasis, urethral catheter, previous urological operation, diabetes mellitus, use of antibiotics during the last 3 months and hospitalization during the last 3 months were investigated as risk factors. The presence of previous urological operation and quinolone or cephalosporin use for any infection during the last 3 months were found to be independent risk factors. Knowing the risk factors for community acquired/onset urinary tract infections caused by ESBL-positive E. coli or K. pneumoniae is of great importance in planning empirical antibiotic therapy.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Anti-Bacterial Agents / therapeutic use
  • Cephalosporins / therapeutic use
  • Community-Acquired Infections
  • Escherichia coli
  • Escherichia coli Infections / drug therapy*
  • Female
  • Humans
  • Klebsiella Infections / drug therapy*
  • Klebsiella pneumoniae
  • Male
  • Middle Aged
  • Quinolones / therapeutic use
  • Risk Factors
  • Urinary Tract Infections / etiology*
  • Urinary Tract Infections / microbiology*
  • Urologic Surgical Procedures
  • beta-Lactamases*

Substances

  • Anti-Bacterial Agents
  • Cephalosporins
  • Quinolones
  • beta-Lactamases