Hepatoid esophageal carcinoma: a rare cause of elevated alpha fetoprotein

J Gastrointest Cancer. 2008;39(1-4):58-60. doi: 10.1007/s12029-008-9043-x. Epub 2009 Jan 16.

Abstract

AFP-producing tumors are uncommon. They have mostly been described of pulmonary origin. However, they have also been described from gastrointestinal tract. Esophageal involvement with hepatoid tumor has been rarely described. The diagnosis is clinically challenging in patients with metastatic disease to liver. We present an interesting case of AFP-producing esophageal tumor, describing its clinical presentation, endoscopic manifestation, as well as histological features.

Publication types

  • Case Reports

MeSH terms

  • Carcinoma, Hepatocellular / chemistry
  • Carcinoma, Hepatocellular / pathology*
  • Esophageal Neoplasms / chemistry
  • Esophageal Neoplasms / pathology*
  • Humans
  • Immunohistochemistry
  • Keratins / analysis
  • Liver Neoplasms / chemistry
  • Liver Neoplasms / pathology*
  • Male
  • Middle Aged
  • alpha-Fetoproteins / analysis*

Substances

  • alpha-Fetoproteins
  • Keratins