Congenital cataract etiology

Tunis Med. 2007 Dec;85(12):1025-9.

Abstract

Aim: Our purpose is to study the aetiologies of congenital cataracts, and to establish an approach to decision making of etiological diagnosis.

Methods: We included 85 children in a cross sectional study. The mean age was 4.5 years. These patients underwent a complete ophthalmologic and paediatric examination, and etiological investigation.

Results: An aetiology of congenital cataracts was found in 62.5% of cases. Hereditary was the most common cause, it constituted 42.3% of etiologies. Among these cases 77.7% were autosomal recessive. 16.4% of congenital cataracts were associated with general diseases or dysmorphology syndromes. Metabolic diseases and intrauterine infections were found in 7 % and 4.7% of cases respectively.

Conclusion: Heredity remains the most common etiology of congenital cataracts.

Publication types

  • Comparative Study

MeSH terms

  • Adolescent
  • Cataract / congenital*
  • Cataract / diagnosis
  • Cataract / etiology
  • Cataract / genetics
  • Child
  • Child, Preschool
  • Chromosome Disorders / complications
  • Cross-Sectional Studies
  • Female
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Metabolic Diseases / complications