Tissue accumulation of aluminium is not a predictor of toxicity in the freshwater snail, Lymnaea stagnalis

Environ Pollut. 2009 Jul;157(7):2142-6. doi: 10.1016/j.envpol.2009.02.009. Epub 2009 Mar 13.

Abstract

The amount of toxic metal accumulated by an organism is often taken as an indicator of potential toxicity. We investigated this relationship in the freshwater snail, Lymnaea stagnalis, exposed to 500 microg l(-1) Al over 30 days, either alone or in the presence of phosphate (500 microg l(-1) P) or a fulvic acid surrogate (FAS; 10 mg l(-1) C). Behavioural activity was assessed and tissue accumulation of Al quantified. Lability of Al within the water column was a good predictor of toxicity. FAS increased both Al lability and behavioural dysfunction, whereas phosphate reduced Al lability, and completely abolished Al-induced behavioural toxicity. Tissue accumulation of Al was not linked to toxicity. Higher levels of Al were accumulated in snails exposed to Al + P, compared to those exposed to Al alone, whereas FAS reduced Al accumulation. These findings demonstrate that the degree of tissue accumulation of a metal can be independent of toxicity.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aluminum / pharmacokinetics
  • Aluminum / toxicity*
  • Animals
  • Behavior, Animal / drug effects
  • Environmental Exposure
  • Lymnaea / drug effects
  • Lymnaea / metabolism*
  • Tissue Distribution
  • Toxicity Tests, Acute
  • Water Pollutants, Chemical / pharmacokinetics
  • Water Pollutants, Chemical / toxicity*

Substances

  • Water Pollutants, Chemical
  • Aluminum