Extreme genome repair

Cell. 2009 Mar 20;136(6):998-1000. doi: 10.1016/j.cell.2009.03.008.

Abstract

Slade et al. (2009) describe in this issue how the genome of the bacterium Deinococcus radiodurans gets reassembled after being shattered by high-dose radiation. In contrast to the extreme nature of the damage, the steps of repair appear surprisingly ordinary. So, why can't all organisms carry out extreme genome repair?

Publication types

  • Comment
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • DNA Damage
  • DNA Repair*
  • Deinococcus / genetics*
  • Deinococcus / radiation effects*
  • Genome, Bacterial