Ageing of the face is one of the most apparent. Face varies in shape and aspect. The reasons of these modifications are various: skin ageing, lost of teeth, changes in facial skeleton and modifications of the whole facial soft tissues. Soft tissues evolution in mentalis and anterior nasal spin regions was studied on a 206, 21 to 101 years old subjects population. It was shown that in both men and women samples the soft tissues thickness increase in the mentalis region and decrease in that of anterior nasal spin.