MicroRNA-124: micromanager of neurogenesis

Thales Papagiannakopoulos; Kenneth S Kosik

doi:10.1016/j.stem.2009.04.007

MicroRNA-124: micromanager of neurogenesis

Cell Stem Cell. 2009 May 8;4(5):375-6. doi: 10.1016/j.stem.2009.04.007.

Authors

Thales Papagiannakopoulos¹, Kenneth S Kosik

Affiliation

¹ Neuroscience Research Institute, University of California Santa Barbara, Santa Barbara, CA 93106, USA.

PMID: 19427286
DOI: 10.1016/j.stem.2009.04.007

Abstract

In a recent issue of Nature Neuroscience, Cheng et al. (2009) demonstrate that miR-124, the most abundant of the microRNAs in the adult brain, positively modulates the transitory progression of adult subventricular zone (SVZ) neurogenesis.

MeSH terms

Adult Stem Cells / cytology*
Animals
Cell Differentiation
Embryo, Mammalian / metabolism
Mice
MicroRNAs / metabolism*
Neurogenesis / physiology*
Stem Cell Niche / cytology
Stem Cell Niche / metabolism

Substances

MicroRNAs
Mirn124 microRNA, mouse