Histomorphometric evaluation of implant design as a key factor in peri-implant bone response: a preliminary study in a dog model

Minerva Stomatol. 2009 Jun;58(6):263-75.
[Article in English, Italian]

Abstract

Aim: Primary implant stability as the establishment of a direct bone-to-implant contact (BIC) plays a major role in long-term successful implant osseointegration. Numerous factors influencing this initial stability have been studied. This preliminary in vivo study on a dog lower jaw aimed to investigate the hypothesis that primary implant stability in low density bone may be influenced by implant design.

Methods: The authors compared two different implant designs with regard to their immediate quantitative relation to host bone (BIC% and gap area, GA%). The screw-shaped implants, manufactured by Or-Vit (Castelmaggiore-Bologna, Italy), exhibited similar microroughness surface and two different thread pitches: ''narrow-pitch'' implants (NP) and ''wide-pitch'' implants (WP) with a 0.5 mm and 1.5 mm thread pitch respectively. Implants were placed in dog jaw after complete osseous healing of the extractive sockets, according to a delayed implantation procedure. Five hours after surgery the animal was sacrificed. Radiographic, histological, morphometric and ultrastructural analysis were performed.

Results: An inverse relation existed among the two parameters BIC and GA: GA, as a region with high osteogenetic potentiality, appeared wider in WP implants; BIC, as the expression of primary mechanical stability, was higher in NP implants.

Conclusion: Based on this results, we could assume that NP implants might be the clinical choice in case of immediate loading.This single case study might be considered a starting point for further long term in vivo investigations aiming to establish the implant design that best favours osseointegration at different bone quality sites.

Publication types

  • Evaluation Study

MeSH terms

  • Animals
  • Bicuspid
  • Dental Implantation
  • Dental Implants, Single-Tooth*
  • Dogs
  • Female
  • Mandible / surgery
  • Mandible / ultrastructure*
  • Microscopy, Electron, Scanning
  • Osseointegration*
  • Pilot Projects
  • Prosthesis Design
  • Surface Properties